Education & Training
Medical School
Washington University School of Medicine
Internship
Internal Medicine
- St. Luke's Hospital
Residency
Diagnostic Radiology
- Beth Israel Deaconess Medical Center
Fellowship
Neuroradiology
- University of California San Francisco
Boards
Insurances
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Academic Information
Office
1 Hospital Dr
Room M288
Columbia, MO 65212
United States
Research Profile
Mai-Lan Ho, MD, is an accomplished neuroradiology physician-scientist and leader specializing in the full scope of advanced imaging. Dr. Ho has clinical expertise in advanced neuroimaging techniques and genotype-phenotype correlation in complex diseases. Her research focus involves radiologic technology development, quantitative image analysis and imaging genomics. Dr. Ho also leads multiple national and international initiatives for data science and precision health and serves on national/international society committees and editorial boards dedicated to advanced imaging and AI.
Dr. Ho’s research program involves the three key focus areas of translational advanced imaging, imaging genomics and artificial intelligence, improving imaging technology, implementation and integration by using clinical and basic sciences. Her independent and collaborative publications/grants apply expertise in medical physics, computer vision and data science for added value in clinical practice. As PI/co-I on several federal, foundation, and industry awards, Dr. Ho has built integrated teams of imaging physicists, referring physicians, radiologists and data scientists to accelerate bench-to-bedside translation.
In her leadership roles, Dr. Ho has created funded infrastructure for imaging investigators supporting task-based and resting-state functional MRI, advanced diffusion, perfusion, elastography, fingerprinting, spectroscopy, vessel wall imaging, ultrashort-echo time, 3D visualization and printing, and machine and deep learning. Actively promoting team science, overseeing innovative curricula and providing academic mentorship to faculty and trainees in various disciplines are core to her scientific principles.
Research Interests
- Interdisciplinary neuroscience
- Artificial intelligence
- Precision health
Areas of Expertise
- Translational advanced imaging
- Imaging genomics
- Pediatric neuroradiology
- Head & neck imaging
Awards & Honors
- 2023 Anne G. Osborn International Outreach Professor, American Society of Neuroradiology
- 2023 Atis K. Freimanis Visiting Professor, Michigan State University
- 2023 John D. Strain Leadership Scholarship, Society of Chiefs of Radiology at Children’s Hospitals
- 2023 Keynote Speaker, University of Colorado Radiology Research Symposium
- 2023 Radiology Management Program, Association of University Radiologists
- 2023 Most Impactful Radiology Research Project, Nationwide Children’s Hospital
- 2023 Entrepreneurship for Biomedicine Program, Washington University in St. Louis
- 2023 Clinical Trials Methodology Workshop, Radiological Society of North America
- 2022 Keynote Speaker, Utrecht Brain Conference
- 2022 Women’s Pilot Workshop, The Academy for Radiology & Biomedical Imaging Research
- 2022 Radiology Continuing Medical Education Award, Nationwide Children’s Hospital
- 2022 Radiology Research Award, Nationwide Children’s Hospital
- 2022 Siemens Healthineers Academy, Siemens Healthineers Asia Pacific
- 2022 Most Cited Award, Doximity
- 2022 Most Published Award, Doximity
- 2022 Top Radiologist, Top Doctors Edition, Ohio Magazine
- 2022 Editor’s Choice Article, Seminars in Pediatric Neurology
- 2022 Paul Dyken Scholarship Lecture, Southern Pediatric Neurology Society
- 2021 Most Published Award, Doximity
- 2021 Radiology Medical Education Grant, Bayer Healthcare
- 2021 CHEST Foundation Research Grant in Cystic Fibrosis, American College of Chest Physicians
- 2021 International Virtual Reading Room Professor, American Society of Neuroradiology
- 2021 Katherine A. Shaffer Award, Radiology Institute Leadership Summit, American Association for Women in Radiology
- 2021 Creating and Optimizing the Research Enterprise, Radiological Society of North America
- 2021 Certificate of Merit, American Society of Neuroradiology
- 2021 Magna Cum Laude Electronic Exhibit, American Society of Neuroradiology
- 2021 Top Radiologist, Top Doctors Edition, Ohio Magazine
- 2021 Medical Leadership Program, Nationwide Children’s Hospital
- 2020 Faculty Leadership Institute, The Ohio State University College of Medicine / Fisher College of Business
- 2020 2nd Place, Artificial Intelligence Research Award, American Society of Neuroradiology / American Society of Functional Neuroradiology
- 2020 Artificial Intelligence Workshop, American Society of Neuroradiology / American Society of Functional Neuroradiology
- 2019 Advanced Course in Grant Writing, Radiological Society of North America
- 2019 Innovation Fund Grant, American College of Radiology
- 2019 Path-Finder Grant, Department of Radiology, Nationwide Children’s Hospital
- 2019 Honorary Member, Pernambuco Radiology Society
- 2019 Anne G. Osborn International Outreach Professor, American Society of Neuroradiology
- 2019 Collaborative Travel Award, Karolinska Institutet
- 2019 Society for Pediatric Radiology Representative, Council of Early Career Investigators in Imaging, The Academy for Radiology & Biomedical Imaging Research
- 2018 William N. Hanafee Award, American Society of Head and Neck Radiology
- 2018 Pilot Award, Society for Pediatric Radiology
- 2018 Siemens Healthineers / Research Scholar Grant, Radiological Society of North America
- 2018 Paul Dyken Scholarship Lecture, Southern Pediatric Neurology Society
- 2017 Summa Cum Laude Educational Exhibit, American Society of Neuroradiology
- 2017 Faculty Development Program, Association of University Radiologists
- 2016 Radiology Research Award, Department of Radiology, Mayo Clinic
- 2016 Advance Award, Department of Radiology, Mayo Clinic
- 2016 Magna Cum Laude Electronic Educational Exhibit, American Society of Neuroradiology
- 2014 Gabriel H. Wilson Award, Western Neuroradiological Society
- 2014 Radiology and Biomedical Imaging Seed Grant, University of California, San Francisco
- 2014 Research Fellow Award, Society for Pediatric Radiology
- 2013 Risa and Felix Fleischner Young Investigator Award, Beth Israel Deaconess Medical Center
- 2012 Roentgen Resident / Fellow Research Award, Radiological Society of North America
- 2012 William W. Olmsted Editorial Fellowship for Trainees, Radiological Society of North America
- 2011 Bracco Diagnostics / Radiological Society of North America Research Resident Grant
- 2011 Excellence in Teaching Award, Harvard Medical School
- 2011 The Academy of Medical Educators, Beth Israel Deaconess Medical Center
- 2011 Resident Research Award, Beth Israel Deaconess Medical Center
- 2011 Lawrie B. Morrison Research Award, Beth Israel Deaconess Medical Center
- 2011 Stephen A. Kieffer Award, Eastern Neuroradiological Society
- 2011 Siemens-AUR Radiology Resident Academic Development Program
- 2011 1st Place Team, AUR-Philips Vydareny Film Interpretation Competition
- 2011 Lucy Frank Squire Distinguished Resident Award in Diagnostic Radiology, American Association for Women in Radiology
- 2008 Hugh M. Wilson Award for Meritorious Work in Radiology, Washington University
- 2008 Best Scientific Presentation, Society of Thoracic Radiology
- 2005 National Institutes of Health Research Fellowship, Washington University School of Medicine
- 2005 National Dean’s List Merit Scholarship, Washington University
- 2004 National Institutes of Health Research Fellowship, Washington University School of Medicine
- 2003 John T. Haslam Fellowship, Massachusetts Institute of Technology
- 2003 American Institute of Chemical Engineers Distinguished Service Award, Stanford University
- 2003 Outstanding Senior Award, American Institute of Chemical Engineers
- 2003 Merck Award for Student Research, Stanford University
- 2002 Phi Beta Kappa Honor Society, Stanford University
- 2002 Tau Beta Pi Honor Society, Stanford University
- 2002 Electronics for Imaging Scholarship, Society of Women Engineers
- 2002 Academic Flagbearer & School of Engineering Representative, Stanford University
- 2002 Engineering & Technology Fellowship / Merit Scholarship, Merck & Co.
- 2002 Howard Hughes Medical Institute Research Fellowship, Stanford University
- 2001 Corporate Fellowship / Merit Scholarship, The Coca-Cola Company
- 2001 Rockwell Corporation Scholarship, Society of Women Engineers
- 2001 Channing Robertson Distinguished Service Award, Stanford University
- 2001 Cap and Gown Honor Society, Stanford University
- 2000 Howard Hughes Medical Institute Research Fellowship, Washington University
- 2000 Dorothy Lemke Howarth Scholarship, Society of Women Engineers
- 1999 Grand Prize Winner, United States of America Mathematical Talent Search
- 1999 Elizabeth Blodgett Hall “Acceleration to Excellence” Scholarship, Simon’s Rock College
Publications
Peer-Reviewed Publications
- Ho ML. Pediatric spine tumors and dysontogenetic masses. In press, Neuroimaging Clin N Am. DOI: 10.1016/j.nic.2023.04.002. Online ahead of print.
- Wang DJJ, Hua J, Cao D, Ho ML. Neurofluids and the glymphatic system: anatomy, physiology, and imaging. Br J Radiol. 2023 Jun 1;20230016. DOI: 10.1259/bjr.20230016. Online ahead of print. PMID: 37191063.
- Lindner T, Achten E, Barkhof F, Bolar DS, Detre JA, Golay X, Günther M, Wang DJJ, Haller S, Ingala S, Jäger HR, Jahng GH, Juttukonda MR, Keil VC, Kimura H, Ho ML, Leite AB, Lequin M, Lou X, Petr J, Pinter N, Pizzini FB, Smits M, Sokolska M, Zaharchuk G, Mutsaerts HJMM. Current state and guidance on arterial spin labeling perfusion MRI in clinical neuroimaging. Magn Reson Med. 2023 May;89(5):2024-2047. PMID: 36695294.
- Ho ML, Arnold CW, Decker SJ, Hazle JD, Krupinski EA, Mankoff DA. Institutional strategies to maintain and grow imaging research during the COVID-19 pandemic. Acad Radiol. 2023 Apr;30(4):631-639. PMID: 36764883. PMCID: PMC9816088.
- Deep NL, Carlson ML, Hoxworth JM, Driscoll CLW, Lohse CM, Lane JI, Ho ML. Classifying the large vestibular aqueduct: morphometry to audiometry. Otol Neurotol. 2023 Jan 1;44(1):47-53. PMID: 36509439.
- Iyer S, Ismail M, Tamrazi B, Salloum R, De Blank P, Margol AS, Correa R, Chen J, Bera K, Statsevych V, Ho ML, Vaidya P, Verma P, Hawes D, Judkins A, Madabhushi A, Tiwari P. Novel MRI deformation-heterogeneity radiomic features are associated with molecular subgroups and overall survival in pediatric medulloblastoma: preliminary findings from a multi-institutional study. Front Oncol. 2022 Dec 21;12:915143. PMID: 36620600. PMCID: PMC9811390.
- Ho ML*, Wirrell EC*, Petropoulou K, Sakonju A, Chu D, Seratti G, Palasis S. Role of electroencephalogram (EEG) and magnetic resonance imaging (MRI) findings in early recognition and diagnosis of neuronal ceroid lipofuscinosis type 2 disease. J Child Neurol. 2022 Dec;37(12-14):984-991. PMID: 36184928.
- Hwang M, Barton K, Kim JS, Machnitz AJ, Holm T, Maianski I, Setty BN, Birkemeier KL, Radhakrishnan R, Sreedher G, Victoria T, Nikam R, Sintim-Damoa A, Ho ML. Utilization of neonatal sedation and anesthesia: an SPR survey. Pediatr Radiol. 2022 Dec;52(13):2630-2635. PMID: 35767032.
- Zamora CA, Huisman TAGM*, Ho ML*. Academic onboarding: a practical guide for the junior, early career radiologist. Acad Radiol. 2022 Dec;29(12):1863-1868. PMID: 35414474.
- Radhakrishnan R, Shea LAG, Pruthi S, Silvera VM, Bosemani T, Desai NK, Gilbert DL, Glenn OA, Guimaraes GV, Ho ML, Lam HFS, Maheshwari M, Mirsky DM, Nadel HR, Partap S, Schooler GR, Udayasankar UK, Whitehead MT, Wright JN, Rigsby CK. ACR Appropriateness Criteria® Ataxia-Child. J Am Coll Radiol. 2022 Nov;19(11S):S240-S255. PMID: 36436955.
- Bambach S, Ho ML. Deep learning for synthetic CT from bone MRI in the head and neck. AJNR Am J Neuroradiol. 2022 Aug;43 (8) 1172-1179. PMID: 36920777. PMCID: PMC9575432.
- Benninger KL, Peng J, Ho ML, Newton J, Wang DJJ, Hu HH, Stark AR, Rusin JA, Maitre NL. Cerebral perfusion and neurological examination characterise neonatal opioid withdrawal syndrome: a prospective cohort study. Arch Dis Child Fetal Neonatal Ed. 2022 Jul;107(4):414-420. PMID: 34725106.
- D'Arco F, Mertiri L, de Graaf P, De Foer B, Popovič KS, Argyropoulou MI, Mankad K, Brisse HJ, Juliano A, Severino M, Van Cauter S, Ho ML, Robson CD, Siddiqui A, Connor S, Bisdas S; Consensus for Magnetic Resonance Protocols Study (COMPS) Group. Correction to: Guidelines for magnetic resonance imaging in pediatric head and neck pathologies: a multicentre international consensus paper. Neuroradiology. 2022 Jun;64(6):1309. PMID: 35488917.
- D'Arco F, Mertiri L, de Graaf P, De Foer B, Popovič KS, Argyropoulou MI, Mankad K, Brisse HJ, Juliano A, Severino M, Van Cauter S, Ho ML, Robson CD, Siddiqui A, Connor S, Bisdas S; Consensus for Magnetic Resonance Protocols Study (COMPS) Group. Guidelines for magnetic resonance imaging in pediatric head and neck pathologies: a multicentre international consensus paper. Neuroradiology. 2022 Jun;64(6):1081-1100. PMID: 35460348.
- Wiesinger F, Ho ML. Zero-TE MRI: principles and applications in the head and neck. Br J Radiol. 2022 Aug 1;95(1136):20220059. PMID: 35616709.
- Chaudhari B, Ho ML. Congenital brain malformations: an integrated diagnostic approach. Semin Pediatr Neurol. 2022 Jul;42:100973. PMID: 35868725.
- Golay X, Ho ML. Multidelay ASL of the pediatric brain. Br J Radiol. 2022 Jun 1;95(1134):20220034. PMID: 35451851.
- Page KM, Ream MA, Rangarajan HG, Galindo R, Mian AY, Ho ML, Provenzale J, Gustafson K, Rubin J, Shenoy S, Kurtzberg J. Benefits of newborn screening and hematopoietic cell transplant in infantile Krabbe disease. Blood Adv. 2022 May 10;6(9):2947-2956. PMID: 35042231. PMCID: PMC9092415.
- Bambach S, Smith M, Morris PP, Campeau NG, Ho ML. Arterial spin labeling applications in pediatric and adult neurologic disorders. J Magn Reson Imaging 2022 Mar;55(3):698-719. PMID: 33314349.
- Kautto EA, Schieffer KM, McGrath S, Miller AR, Hernandez-Gonzalez ME, Choi S, Conces MR, Fernandez-Faith E, Ho ML, Lee K, Lillis AP, Pearson GD, Kaler SG, Wilson RK, Mardis ER, Magrini V, Leonard J, Cottrell CE. Expanding the clinical phenotype of FGFR1 internal tandem duplication. Cold Spring Harb Mol Case Stud. 2022 Mar 24;8(2):a006174. PMID: 35149534. PMCID: PMC8958921.
- Matarneh B, Cottrell C, Choi S, Pearson G, Fung B, Koo SC, Lillis A, Ho ML*, Fernandez Faith E*. KRIT1-positive hyperkeratotic cutaneous capillary venous malformation. Pediatr Dermatol. 2022 Mar;39:250–254. PMID: 34964173.
- Abreu NJ, Siemon AE, Baylis AL, Kirschner RE, Pfau RB, Ho ML, Hickey SE, Truxal KV. Novel truncating variant in KMT2E associated with cerebellar hypoplasia and velopharyngeal dysfunction. Clin Case Rep. 2022 Feb 11;10(2):e05277. PMID: 35169466. PMCID: PMC8832165.
- Ho ML. Pediatric neck masses: imaging guidelines and recommendations. Radiol Clin North Am. 2022 Jan;60(1):1-14. PMID: 34836558.
- Maddu K, Amin P, Jalal S, Mauricio C, Norbash A, Ho ML, Sanelli PC, Ali IT, Shah S, Abujudeh H, Nicolaou S, Bencardino J, Khosa F. Gender disparity in radiology society committees and leadership in North America and comparison with other continents. Curr Probl Diagn Radiol. Nov-Dec 2021;50(6):835-841. PMID: 33067072.
- Rees MA, Squires JH, Coley BD, Hoehne B, Ho ML. Ultrasound of congenital spine anomalies. Pediatr Radiol. 2021 Dec;51(13):2442-2457. PMID: 34532816.
- Mansukhani S, Ho ML, Brodsky MC. Abnormal vestibular-ocular reflexes in children with cortical visual impairment. J Neuroophthalmol. 2021 Dec 1;41(4):531-536. PMID: 32672437.
- Deelchand DK, Ho ML, Nestrasil I. Ultra-high-field imaging of the pediatric brain and spinal cord. Magn Reson Imaging Clin N Am. 2021 Nov;29(4):643-653. PMID: 34717851.
- Kobayashi N, Bambach S, Ho ML. Ultrashort echo-time MR imaging of the pediatric head and neck. Magn Reson Imaging Clin N Am. 2021 Nov;29(4):583-593. PMID: 34717846.
- Wang DJJ, Le Bihan D, Krishnamurthy R, Smith M, Ho ML. Noncontrast pediatric brain perfusion: arterial spin labeling and intravoxel incoherent motion. Magn Reson Imaging Clin N Am. 2021 Nov;29(4):493-513. PMID: 34717841.
- Ho ML. Advanced pediatric neuroimaging: “better, stronger, faster.” Magn Reson Imaging Clin N Am. 2021 Nov;29(4):xvii-xviii. PMID: 34717854.
- Koboldt DC, Miller KE, Miller AR, Bush JM, McGrath S, Leraas K, Crist E, Fair S, Schwind W, Wijeratne S, Fitch J, Leonard J, Shaikhouni A, Hester ME, Magrini V, Ho ML, Pierson CR, Wilson RK, Ostendorf AP, Mardis ER, Bedrosian TA. PTEN somatic mutations contribute to spectrum of cerebral overgrowth. Brain. 2021 Nov 29;144(10):2971-2978. PMID: 34048549.
- Kirsch CE, Ho ML. Advanced magnetic resonance imaging of the skull base. Semin Ultrasound CT MR. 2021 Jun;42(3):229-252. PMID: 34147160.
- Abreu NJ, Selvaraj B, Moore-Clingenpeel M, Truxal KV, Zumberge NA, McNally K, McBride KL, Ho ML, Flanigan KF. Longitudinal MRI brain volume changes over one year in children with mucopolysaccharidosis types IIIA and IIIB. Mol Genet Metab. 2021 Jun;133(2):193-200. PMID: 33962822.
- Serai SD, Ho ML, Artunduaga M, Can SS, Chavhan GB. Components of a magnetic resonance imaging system and their relationship to safety and image quality. Pediatr Radiol. 2021 May;51(5):716-723. PMID: 33871725.
- Sreedher G, Ho ML, Smith M, Udayasankar U, Risacher S, Rapalino O, Greer ML, Doria A, Gee MS. Magnetic resonance imaging quality control, quality assurance and quality improvement. Pediatr Radiol. 2021 May;51(5):698-708. PMID: 33772641.
- Smith M, Bambach S, Selvaraj B, Ho ML. Zero-TE MRI: potential applications in the oral cavity and oropharynx. Top Magn Reson Imaging. 2021 Apr 1;30(2):105-115. PMID: 33828062.
- Parthasarathy J, Sribnick E, Ho ML, Beebe A. Customized hybrid CT-MRI 3D-printed model for grade V spondylolisthesis in an adolescent. BMJ Case Rep. 2021 Mar 1;14(3):e239192. PMID: 33649040. PMCID: PMC7929802.
- Mark IT, Black DF, DeLone DR, Passe TJ, Witte RJ, Little JT, Ho ML, Fagan AJ, Parney IF, Burns TC, Welker KM. Higher temporal resolution multiband fMRI provides improved presurgical language maps. Neuroradiology. 2021 Mar;63(3):439-445. PMID: 33025042.
- Myers L, Ho ML, Cauvet E, Lundin K, Carlsson T, Kuja-Halkola R, Tammimies K, Bölte S. Actionable and incidental neuroradiological findings in twins with neurodevelopmental disorders. Sci Rep. 2020 Dec 29;10(1):22417. PMID: 33376247. PMCID: PMC7772336.
- Becker M, Mastropasqua F, Reising JP, Maier S, Ho ML, Rabkina I, Li D, Neufeld J, Ballenberger L, Myers L, Moritz V, Kele M, Wincent J, Willfors C, Sitnikov R, Herlenius E, Anderlid BM, Falk A, Bölte S, Tammimies K. Presynaptic dysfunction in CASK-related neurodevelopmental disorders. Transl Psychiatry. 2020 Sep 14;10(1):312. PMID: 32929080.
- Ho ML, Eschbacher KL, Paolini MA, Raghunathan A. New insights into calcifying pseudoneoplasm of the neuraxis (CAPNON): a 20-year radiological-pathological study of 37 cases. Histopathology. 2020 Jun;76(7):1055-1069. PMID: 31955449.
- Jones JY, Selvaraj B, Ho ML. Pediatric functional neuroimaging: practical tips and pearls. AJR Am J Roentgenol. 2020 May;214(5):995-1007. PMID: 32228326.
- Ho ML, Mansukhani S, Brodsky MC. Prenatal or perinatal injury? Diagnosing the cortically blind infant. Am J Ophthalmol. 2020 Mar;211:56-62. PMID: 31704229.
- Wilton KM, Morales-Rosado JA, Muthusamy K, Ewing S, Agre K, Selcen D, Nickels K, Klee EW, Ho ML*, Morava E*. Developmental brain abnormalities and acute encephalopathy in a patient with myopathy with extrapyramidal signs secondary to pathogenic variants in MICU1. JIMD Rep. 2020 Mar 20;53(1):22-28. PMID: 32395406.
- Yamazaki Y, Urrutia R, Franco LM, Giliani S, Zhang K, Alazami AM, Dobbs AK, Masneri S, Joshi A, Otaizo-Carrasquero F, Myers TG, Ganesan S, Bondioni MP, Ho ML, Marks C, Alajlan H, Mohammed RW, Zou F, Valencia CA, Filipovich AH, Facchetti F, Boisson B, Azzari C, Al-Saud BK, Al-Mousa H, Casanova JL, Abraham RS, Notarangelo LD. PAX1 is essential for development and function of the human thymus. Sci Immunol. 2020 Feb 28;5(44). PMID: 32111619.
Books
- Arroyo H, Torres A, Vidaurre J, Rugilo C, Ho ML, eds. Clinical and Imaging Case Studies in Pediatric Neurology. Cambridge Scholars Publishing, 2023.
- Ho ML, ed. Pediatric Neuroimaging: State-of-the-Art. MRI Clinics of North America, 2021.
- Ho ML, ed. The AAWR Pocket Mentor. American Association for Women in Radiology, 2021.
Book Chapters
- Arroyo H, Torres A, Vidaurre J, Rugilo C, Ho ML. Headache. In: Clinical and Imaging Case Studies in Pediatric Neurology. Cambridge Scholars Publishing, 2023.
- Ho ML, Moonis G, Bunch PM. Cochlear promontory lesions. In: Small JE, Schaefer PS, Sarma A, Bunch PM, eds. Neuroradiology: Key Differential Diagnoses and Clinical Questions. Saunders, 2nd ed., 2023.
- Ho ML, Bunch PM, Moonis G. Lesions of the facial nerve. In: Small JE, Schaefer PS, Sarma A, Bunch PM, eds. Neuroradiology: Key Differential Diagnoses and Clinical Questions. Saunders, 2nd ed., 2023.
- Ho ML. Avoiding pitfalls in pediatric spine imaging. In: Kennedy TA, Leyendecker JR, Phillips GS, eds. Strategies to Overcome the Most Common Misses in Clinical Practice. American Roentgen Ray Society, 2020.
- Deep NL, O’Connell BP, Ho ML, Lane JI, Carlson ML. Surgery for cochlear implantation–congenital anomalies. In: Haynes DS, Gifford RH, Wanna GB, Rivas AC, eds. Cochlear Implants: From Principles to Practice. JP Brothers, 2020.